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PROBIOTICS 101: NOT ALL STRAINS ARE CREATED EQUAL

Jan. 19, 2012


by Daniel Pierce

There is no doubt about it, probiotics are not another flash in the pan ingredient. Year by year, their presence has increased across all sales channels and research dollars have continued to accelerate into this burgeoning ingredient market. Experts can agree that as public awareness grows about the benefits of both gastrointestinal and immune health ingredients , these condition specific ingredients will continue to be on the rise, especially probiotics.

One common misconception about probiotics is that you need 5, 10, 20 billion colony forming units (CFU) for them to be effective. While that has proven to be true for some strains, Ganeden BC30 (Bacillus coagulans GBI-30, 6086) has been proven in a clinical setting in healthy humans at 500 million CFU. The facts are hard to overlook.

product type claim probiotic strain dose (cfu)
MyoFusion and Real Mass Probiotic Series Supports immune & digestion health GanedenBC30 (Bacillus coagulans GBI-30, 6086) 500 million - 1 billion
Popular Yogurt Supports immune & digestion health Bifidobacterium animalis 10 billion
Popular Nutrition Bar Supports immune & digestion health Lactobacillus acidophilus 6.1 billion
Popular Fruit Drink Supports immune & digestion health L. plantarum 20 billion
Popular Cultured Milk Supports immune & digestion health L. casei 8 billion
Popular Capsulated Product Maintains healthy intestinal function Saccharomyces boulardii 5 billion
Popular Capsulated Product Promotes good digestion and enhances immune system Lactobacillus rhamnosus 10 billion
Bacillus coagulans are surrounded by a natural protective shield. This protective layer helps Bacillus coagulans survive the heat and pressure of manufacturing and the acids in the stomach in order to reach the intestines, their intended target. Other traditional probiotic bacteria, such as bifidobacterium and lactobacillus, do not contain this protective outer shell and therefore may not survive.
Bacillus coagulans are spore-forming bacteria that can be compared to a seed. When left alone, the seed is dormant - meaning to say it’s not alive, yet it’s not dead either. When this seed is put into the right temperature and moisture, it starts to germinate, or grow. Just as a seed waits for the proper conditions to start growing, so does the spore forming bacteria, Bacillus coagulans. However, for Bacillus coagulans, these conditions are met in the body’s intestinal tract. Here, the spore-forming bacteria meet the right temperature and moisture where they begin to grow and colonize - two critical factors for any probiotic bacteria.
Most probiotic bacteria lack effective stability. Stability is the step in the manufacturing or fermentation of the organism that helps to ensure adequate shelf life. Some probiotic manufacturers use special additives to promote some measure of stability and others rely on refrigeration to accomplish this objective. But the harsh reality is that very few of the probiotic products on the market today have any real measure of long term stability.
The ability of the probiotic to effectively colonize or take up temporary residence in the intestines is the end goal of use of probiotic products. Most probiotics are destroyed by gastric acid during ingestion. In addition, bile acid and some enzymes are inhibitory to these organisms and their respective numbers are depleted as a result. Fortunately, research has shown that Bacillus coagulans has an extremely high survivability percentage which has been demonstrated in various testing models. These same tests indicated a strong correlation with increased carbohydrate and protein absorption as well.

In the end, Bacillus coagulans is starting to surface as one of the truly effective leaders within the probiotic market. With all the great clinical data, safety assessments including self-affirmed GRAS status, the great survivability assessments, and room temperature shelf stability, it wasn’t a hard choice to include GanedenBC30 (Bacillus coagulans GBI-30, 6086) in Myofusion Probiotic Series. You expect the best from Gaspari Nutrition and we delivered.
References: 1. Research in Microbiology. 2006 Oct;157(8):720-725. 2. Journal of Bacteriology. 2006 Mar;188(5):1979-86. 3. Journal of Dairy Science. 1997 Jun;80(6):1031-7. 4. FEMS Immunology & Medical Microbiology. 2001 Jul;31(1):35-9 5. Food & Chemical Toxicology. 2011 May;49(5):1174-82. 6. Anaerobe. 2011 Feb;17(1):36-42. 7. Beneficial Microbes. 2010 Mar;1(1):31-6. 8. Postgraduate Medicine. 2009 Mar;121(2):114-8. 9. Food & Chemical Toxicology. 2009 Jun;47(6):1231-8 10. Gastroenterology & Endoscopy News. 2010 June; 61(6):1-8

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